Dear my friends and fellow Colleagues, Both metformin and vildagliptin had similar protective effects on the 1) Beta-cell function, 2) Reduced insulin resistance 3) Glycemic levels. Improved insulin sensitivity was seen with metformin as Metformin is an Insulin Sensitizer. ADA, Virtual Scientific Sessions, June 2020, Abstract 970-P. Regards and thanks, Dr Sepuri Krishna Mohan.