Ayurveda and Yoga can certainly play a pivotal role to augment preventive measures provided in the guidelines by Ministry of Health and Family Welfare (M0HFW). The current understanding of COVID-19 indicates that good immune status is vital to prevention and to safeguard from disease progression. Following three aspects are considered while preparing this protocol: 1. Knowledge from Ayurveda classics and experience from clinical practices 2. Empirical evidences and Biological plausibility 3. Emerging trends of ongoing clinical studies